Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-induced hypertension
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چکیده
منابع مشابه
Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-induced hypertension.
Hyperhomocysteinemia (HHcy) has been observed to promote hypertension, but the mechanisms are unclear. Toll-like receptor 4 (TLR-4) is a cellular membrane protein that is ubiquitously expressed in all cell types of the vasculature. TLR-4 activation has been known to promote inflammation that has been associated with the pathogenesis of hypertension. In this study we hypothesize that HHcy induce...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Cell Physiology
سال: 2016
ISSN: 0363-6143,1522-1563
DOI: 10.1152/ajpcell.00088.2016